This course has the objective of acquainting the students with typical biochemical processes, enzyme kinetics and industrial application, cell kinetics and fermenter design. 1. Biotechnology and Biochemical Engineering  Applications of Biotechnology  Typical Biological Processes 2. Enzyme Kinetics  Commercial Applications of Enzymes  Simple Enzyme Kinetics  Evaluation of Kinetic Parameters  Enzyme Reactor with Simple Kinetics  Inhibition of Enzyme Reactions and Other influences on Enzyme Activity 3. Immobilized Enzyme  Immobilization Techniques  Effect of Mass-Transfer Resistance 4. Industrial Applications of Enzymes  Carbohydrates  Starch Conversion  Cellulose Conversion 5. Cell Kinetics and Fermenter Design  Growth Cycle for Batch Cultivation  Stirred-tank Fermenter  Multiple Fermenters Connected in Series  Cell Recycling  Alternative Fermenters  Structured Model 6. Sterilization  Sterilization Methods  Thermal Death Kinetics  Design Criterion  Batch, Continuous and Air Sterilization 7. Agitation and Aeration  Basic Mass-Transfer Concepts  Correlation for Mass-Transfer Coefficient  Shear-Sensitive Mixing 8. Downstream Processing  Solid-Liquid Separation  Cell Rupture  Recovery and Purification

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